Mississippi Pot Roast Slow Cooker

Section: Satisfying Main Dishes for Every Occasion

Mississippi pot roast combines slow cooked beef chuck with ranch and onion seasoning, butter, and tangy peperoncini peppers for a truly tender, flavorful main dish. The method is simple—brown the roast, layer with seasonings and butter, add peppers, and let the slow cooker work its magic on low. No extra liquid is required as the juicy beef and butter create a luscious sauce. Serve shredded over mashed potatoes or rolls, paired with your choice of vegetables for a deeply comforting meal enjoyed by families for years.

A woman wearing a chef's hat and apron.
Brought to You By nina
Last updated on Tue, 15 Jul 2025 21:31:48 GMT
A plate of Mississippi pot roast with green beans and biscuits. Bookmark
A plate of Mississippi pot roast with green beans and biscuits. | ninatable.com

Mississippi pot roast is a true family favorite in my home because it delivers rich comforting flavor with almost no hands-on effort The beef turns fall-apart tender as it slow cooks with ranch seasoning onion soup mix butter and those distinctive tangy peperoncini peppers Even picky eaters come back for seconds and it never fails to make the whole house smell incredible

I first discovered this while hunting for a new Sunday dinner option and it instantly became a staple My kids ask for Mississippi pot roast every birthday and it is our favorite comfort food

Ingredients

  • Chuck roast: Make sure it is fresh not frozen for even tenderness Choose one with good marbling for best results
  • Ranch dressing mix: Adds creamy tang and seasoning Pick homemade or low sodium to control salt
  • Onion soup mix: Brings depth and classic savory flavor Homemade or low sodium works well
  • Salted butter: Creates richness and melds everything together Choose high quality real butter like Kerrygold for extra flavor
  • Peperoncini peppers: Give bright flavor and a little sparkle to the sauce Look for firm peppers packed in brine for freshness
  • Salt and pepper: Enhance flavors and let you season to taste Use freshly ground pepper for best results

Step-by-Step Instructions

Prepare the Roast:
Dry the chuck roast thoroughly with paper towels then season both sides lightly with salt and pepper This helps the roast brown well and locks in flavor
Brown the Meat:
Heat a large skillet until very hot Add a little oil and sear the roast for two to three minutes per side until golden brown Browning gives depth to the final dish but you can skip this if you prefer
Layer in the Slow Cooker:
Transfer seared roast to the crock pot Sprinkle the ranch dressing mix and onion soup mix evenly over the top Lay the stick of butter right on top then nestle the peperoncini peppers around and on the roast
Slow Cook to Tender Perfection:
Cover the slow cooker and set on low for eight hours Do not lift the lid or add any extra liquid during cooking The meat and peppers produce all the moisture needed
Shred and Serve:
Once cooked use two forks to shred the roast right in the pot Discard large fatty pieces If you love the tangy peppers chop them up and mix in Serve hot over mashed potatoes rice or on a sandwich roll
A plate of food with a green bean, a piece of meat, and a roll.
A plate of food with a green bean, a piece of meat, and a roll. | Ninatable.com

Pepperoncini peppers provide zesty flavor without real spice so the dish stays family friendly My favorite version uses a garlicky butter and homemade ranch mix which feels extra special I will never forget the time we served this at a big family reunion and the crock pot was empty before people finished lining up

Storage tips

Leftover Mississippi pot roast keeps well in the fridge for up to four days Let it cool completely then store in a tightly sealed container For longer storage freeze individual portions for easy lunches or dinners later Remember to defrost overnight in the fridge and gently reheat with a splash of beef broth to keep it moist

Ingredient substitutions

If you need to swap out ingredients try a rump roast or sirloin tip instead of chuck Roast with similar marbling will stay tender For less sodium use homemade blends for the ranch and onion soup mix You can use unsalted butter for more control or try a garlic herb variety for extra flavor If you like some heat add a drizzle of pepperoncini brine or a pinch of crushed red pepper

Serving suggestions

This pot roast goes perfectly over creamy mashed potatoes buttery egg noodles or steamed rice On busy weeknights I also love piling it on toasted rolls with sharp provolone cheese for the best sandwiches Fresh green beans or roasted carrots make a great simple side

A pot of Mississippi pot roast with peppers.
A pot of Mississippi pot roast with peppers. | Ninatable.com

Cultural or historical context

Mississippi pot roast comes from the American South where chuck roast and slow cooking are classic comfort food traditions It gained popularity in the 2000s as a flavorful fix it and forget it meal It is a treasured church supper dish and beloved for its almost miraculous use of a few pantry ingredients to make a heartwarming dinner

Common Recipe Questions

→ Why is slow cooking essential for tender meat?

Slow cooking ensures the roast becomes melt-in-your-mouth tender, allowing the connective tissues to break down without drying out the beef.

→ Can I make my own seasoning blends?

Yes, try blending your own ranch and onion soup mixture for control over salt and flavor, or opt for low-sodium alternatives if preferred.

→ What sides pair well with this dish?

Serve the tender beef over mashed potatoes, rice, or soft rolls. Add sides like green beans, carrots, broccoli, or homemade biscuits for a complete meal.

→ Is butter necessary, or can I substitute it?

Butter adds rich flavor and helps create the signature sauce. Margarine is not recommended as it lacks the same depth.

→ Can I use other cuts of beef?

While chuck roast is ideal, sirloin tip or rump roast also works well—just choose a cut that shreds easily when slow cooked.

→ How do peperoncini peppers affect the dish?

Peperoncini peppers bring a unique tang and depth without making the beef spicy. If necessary, dill pickles are a possible substitute for flavor.

Mississippi Pot Roast Slow Cooker

Slow cooked beef with ranch, onion, butter and mild peppers for a rich, hearty Southern comfort meal.

Prep Time
15 minutes
Cooking Time
480 minutes
Total Time
495 minutes
Brought to You By: nina

Recipe Category: Main Dishes

Skill Level: Great for Beginners

Cuisine Type: American

Portions: 8 Serves (Serves 8 portions)

Dietary Preferences: ~

What You'll Need

→ Main Ingredients

01 1.5–2 kilograms beef chuck roast, fresh and thawed
02 2 tablespoons ranch dressing mix
03 3 tablespoons onion soup mix (or au jus gravy mix)
04 110 grams salted butter (one stick), cut into pieces
05 6–8 whole peperoncini peppers, drained
06 Salt, to taste
07 Freshly ground black pepper, to taste
08 15 millilitres vegetable oil, for searing

Steps to Follow

Step 01

Pat the beef chuck roast with paper towels until thoroughly dry on all sides to promote even browning.

Step 02

Lightly season both sides of the beef with salt and freshly ground black pepper. Heat the vegetable oil in a large skillet over high heat. Once oil shimmers, sear the roast for 2–3 minutes per side, until each surface develops a golden crust.

Step 03

Transfer browned beef chuck roast to the insert of a slow cooker, positioning it in the centre.

Step 04

Sprinkle ranch dressing mix and onion soup mix evenly over the roast. Place butter pieces on top. Add whole peperoncini peppers on and around the roast.

Step 05

Cover with the lid. Set the slow cooker to low and cook for 8 hours, undisturbed. Do not lift the lid during the cooking period.

Step 06

After 8 hours, remove lid. Using two forks, shred the beef directly in the cooker, discarding large fatty pieces. If desired, chop the peperoncini and mix into the meat. Serve hot over mashed potatoes, rice or bread.

Extra Suggestions

  1. For best results, refrain from opening the slow cooker during cooking as heat loss can prevent the beef from becoming tender.
  2. Homemade ranch and onion soup seasoning can be used to control sodium content.
  3. Peperoncini add depth and balance to the dish, not heat. For a slight kick, a splash of their brine can be included.
  4. Leftovers freeze well for up to two months; store in airtight freezer-safe bags after cooling.

Tools You’ll Need

  • Large skillet
  • Slow cooker (minimum 4.5 litre capacity)
  • Paper towels
  • Tongs
  • Two forks

Allergy Details

Read ingredient lists for allergens carefully, and consult a healthcare provider if you're unsure.
  • Contains milk and milk products (butter, ranch and onion soup mixes may have dairy derivatives)

Nutritional Details (Per Serving)

The provided nutrition information is for guidance and shouldn't replace expert medical advice.
  • Calories: 440
  • Fat: 32 grams
  • Carbohydrates: 3 grams
  • Proteins: 36 grams